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Peth in whole blood LC-MS/MS
PEth in whole blood LC-MS/MS
Measurand
- PLPEth (1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol)
- PLPEth-D5
- POPEth (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol)
- POPEth-D5
Benefits
- PLPEth and POPEth
- 6 lyophilised calibrators – Covering the full clinically relevant concentration range
- 3 lyophilised controls – Low, mid, and high levels for reliable quality assurance
- Lyophilised standards are single-use and offer extended shelf life
PEth Analysis in Whole Blood
This innovative LC-MS kit enables the measurement of both 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol (PLPEth) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (POPEth) in whole blood samples — offering a unique and comprehensive approach to detecting (chronic) alcohol consumption. As the first fully commercial solution on the market, this kit delivers accuracy, reliability, and ease of use in one standardised format.
Unique: Total PEth Analysis
Unlike conventional methods that focus solely on PLPEth, this kit allows for the simultaneous measurement of both PLPEth and POPEth, providing a more complete picture of phosphatidylethanol concentrations in whole blood and alcohol intake over time.
Designed for Alcohol Monitoring
PEth is a well-established biomarker for assessing (chronic) alcohol use. This kit supports applications in:
Addiction care
Forensic toxicology
Pre-transplant screening
Occupational and traffic medicine
Lyophilised standards are single-use and offer extended shelf life – Ensuring efficiency and hygiene in routine laboratory workflows
Ready for LC-MS analysis – Optimised for use on standard LC-MS platforms
Technical data
| Simple Precision (CV%) | Control I: |
|---|---|
| PLPEth 2.7 % (20 ng/ml) | |
| POPEth 4.1 % (20 ng/ml) | |
| Control III: | |
| PLPEth 2.1 % (400 ng/ml) | |
| POPEth 1.7 % (400 ng/ml) | |
| Patient: | |
| PLPEth 3.3 % (42 ng/ml) | |
| PLPEth 1.8 % (361 ng/ml) | |
| PLPEth 3.2 % (1 ng/ml) | |
| POPEth 2.1 % (120 ng/ml) | |
| POPEth 2.5 % (1348 ng/ml) | |
| POPEth 2.6 % (58 ng/ml) | |
| Complex Precision (CV%) | Control I: |
| PLPEth 5.3 % (20 ng/ml) | |
| POPEth 7.8 % (20 ng/ml) | |
| Control II: | |
| PLPEth 5.3 % (400 ng/ml) | |
| POPEth 4.6 % (400 ng/ml) | |
| Patient: | |
| PLPEth 10.5 % (12 ng/ml) | |
| POPEth 9.9 % (47 ng/ml) | |
| Limit of Quantification | PLPEth 10.12 ng/ml |
| POPEth 9.54 ng/ml | |
| Linearity | PLPEth 1400 ng/ml |
| POPEth 1680 ng/ml |
More info?
Contact us for more information about this product using the contact form or the contact information below.
Contact details
De Plassen 4
9902 SE Appingedam
The Netherlands