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LCMS - Psychotropic Medication 2 Neuroleptics TDM

Psychotropic Medication 2 (Neuroleptics) Reagent set

SKU: 4070 P PS2

The advantages of the Psychotropic Medication 2 Neuroleptics Reagent kit for LC-MS/MS:

  • Balanced panel for cost reducing and optimal chromatography with optimized mobile phases
  • Simple and improved column life sample preparation without SPE or LLE
  • Internal standard for all components

Components

  • Aripiprazole
  • Clozapine
  • Haloperidol
  • Olanzapine
  • Quetiapine
  • Risperidone
  • 9-OH-risperidone (paliperidone)

At a glance

  • Matrix: Serum
  • Technique: LC-MS/MS
  • Internal Standard: Olanzapine D3,Clozapine D4, Haloperidol D4, Quetiapine D8, Risperidon D4, 9-OH-risperidon D4, Aripiprazole D8

Intended Use



The Diagnotix Psychotropic Medication 2 LC-MS Reagent Kit is designed to determine the concentration of one or more of the listed Neuroleptic analytes and metabolites in serum or plasma as a basis for further diagnostics.



Technical Benefits


  1. Balanced panel: The most abundant compounds and their common metabolites are chosen to ensure that the panel is not too large, but still meets the challenges of routine use. The larger the panel, the more costs are involved to include all analytes and their isotopes, but also more trade-offs must be made for chromatographic optimization.
  2. Column and LC-MS friendly: Mobile phases are optimized for these compounds and for increase column life time. Also, only a small injection volume is required for most systems.
  3. Cost-effective and fast automatable sample preparation: No more SPE or LLE is needed.



Why moving over from HPLC-UV to LC-MS?


By switching to LC-MS, you immediately save on the use of SPE or LLE, longer sample preparation and therefore labor costs. In addition, the runtime of your method is probably shorten and you do not have to worry about interfering other drugs, as long as they do not share the same mass transitions.And because baseline separations are no longer necessary and the mobile phases do not have to contain high concentration buffers, you benefit from a much longer column life.


Especially interesting for laboratories that:


I. Have regular (large) batches of neurolepics patient samples and have a reliable automatable workflow.

II. Already have an LC-MS system, but still perform TDM or neuroleptics analyses on HPLC-UV machines. Eliminating the use of your HPLC-UV system will immediately improve operational efficiency and reduce overall maintenance costs.


Contact Us for More Information


Interested in learning more about our Psychotropic Medication 2 solution for Neurleptics? Contact us via the contact form below. We looking forward to hear from you!

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Contact details

De Plassen 4
9902 SE Appingedam
The Netherlands

info@diagnotix.com +31 (0)596 20 10 62

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